APLIKASI SPEKTROSKOPI INFRAMERAH UNTUK ANALISIS TANAMAN DAN OBAT HERBAL
DOI:
https://doi.org/10.15294/.v0i0.15Keywords:
spektroskopi inframerah, obat herbal, tanaman obatAbstract
Sebagai negara tropis, Indonesia kaya akan keanekaragaman hayati, termasuk diantaranya adalah tumbuhan obat. Tumbuhan obat merupakan bahan dasar untuk pembuatan obat-obatan herbal. Untuk mendapatkan obat-obatan herbal yang berkualitas, pengetahuan tentang komponen-komponen aktif di dalamnya baik secara kualitatif maupun kuantitatif mutlak diperlukan. Spektroskopi inframerah merupakan salah satu metode alternatif untuk analisis produk herbal. Metode ini memiliki beberapa keunggulan diantaranya cepat, preparasi sampel yang mudah, dan bersifat non-destruktif. Seringkali metode ini dikombinasikan dengan kemometri untuk mendapatkan hasil analisis yang akurat. Metode ini mampu memberikan hasil yang valid sebagaimana diperoleh dari metode kromatografi atau spektrofotometri UV. Aspek kecepatan dan kepraktisan metode spektroskopi inframerah ini menjadikannya cocok untuk diterapkan pada analisis rutin, seperti untuk keperluan pengendalian mutu (quality control) pada industri obat-obatan herbal.
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Cen, H., & He, Y. (2007). Theory and application of near infrared reflectance spectroscopy in determination of food quality. Trends in Food Science & Technology, 18(2), 72–83.
Chakraborty, D. (2016). Instrumentation of FTIR and its herbal. World J Pharm Pharmaceutical Sci, 5(3), 498–505.
Chan, C. O., Chu, C. C., Mok, D. K., Daniel, K. W., & Chau, F. T. (2007). Analysis of berberine and total alkaloid content in Cortex Phellodendri by near infraredspectroscopy (NIRS) compared with high-performance liquid chromatography coupled with ultra-visible spectrometric detection. Anal Chim Acta, 592, 121–131.
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Chen, Y., Xie, M. Y., Zhang, H., Wang, Y. X., Nie, S. P., & Li, C. (2012). Quantification of total polysaccharides and triterpenoids in Ganoderma lucidum and Ganoderma atrum by near infrared spectroscopy and chemometrics. Food Chem, 135, 268–275.
Dev, S. (2006). A Selection of Prime Ayurvedic Plant Drugs: Ancient‐ Modern Concordance. Anamaya Publisher.
Ding, N. Y., Li, W., Feng, X. W., & Zhu, Z. L. (2008). Classification and identification of Chinese traditional medicines with NIR diffuse reflection. Comput Appl Chem, 25, 499–502.
Duan, L. Q., Cui, B. H., & Liu, S. F. (2010). Identification of Chinese medicine pieces with similar appearance of formulations drug decoction. Chin J Clin Ration Drug Use, 3, 75–76.
Gimet, R., & Luong, A. T. (1987). Quantitative determination of polymorphic forms in a formulation matrix using the near infra- red reflectance analysis technique. J Pharm Biomed, 5, 205–211.
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Koobkokkruad, T., Chochai, A., Kerdmanee, C., & De‐Eknamul, W. (2007). TLC densitometeric analysis of artemisinin for rapid screening of high producing plantlets of Artemisia annua L. Phytochem Anal, 18, 229–234.
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Lestari, H. P., Martono, S., Wulandari, R., & Rohman, A. (2017). Simultaneous analysis of Curcumin and demethoxycurcumin in Curcuma xanthorriza using FTIR spectroscopy and chemometrics. International Food Research Journal, 24(5), 2097–2101.
Li, W., Cheng, Z., Wang, Y., & Qu, H. (2013). Quality control of Lonicerae Japonicae Flos using near infrared spectroscopy and chemometrics. Journal of Pharmaceutical and Biomedical Analysis, 72, 33–39.
Li, W. H., & Qu, H. B. (2010). Rapid quantification of phenolic acids in Radix Salvia miltrorrhiza extract solutions by FT-NIR spectroscopy in transflective mode. J Pharm Biomed, 52, 425–431.
Li, W. H., Xing, L. H., Fang, L. M., Wang, J., & Qu, H. B. (2010). Application of near infrared spectroscopy for rapid analysis of intermediates of tanreqing injection. J Pharm Biomed, 53, 350–358.
Li, W. L., Liu, S. Y., Xue, D. S., & Qu, H. B. (2010). Rapid analysis of bear gall powder extracts with near infrared diffused reflectance spectroscopy. Journal of Chinese Pharmaceutical Sciences, 45(19), 1500–1503.
Li, Z. S., Mu, J., Dong, L. R., Yin, M., & Shi, M. Z. (2009). Situation analysis of 30 kinds of false and bad Chinese medicines (pieces). Yunnan J Tradit Chin Med Mater, 30, 29–31.
Liu, C., Mishra, A., & Tan, R. (2006). Repellent, insecticidal and phytotoxic activities of isoallantolactone from Inula racemosa. Crop Prot, 25, 508–511.
Liu, H., Zhou, Q., Sun, S.-Q., & Bao, H.-J. (2010). Discrimination of different Chrysanthemums with Fourier transform infrared spectroscopy. J Mol Struct, 90, 1071–1080.
Liu, L. L., Xing, W. X., Jia, N., Lin, P. Y., Mi, H. M., & Wu, Y. T. (2002). Identification of red kojie with elustering analysis by near- infrared diffuse reflectance spectrometry. Acad J Second Mil Med Univ, 23, 1230–1232.
Liu, S., Zhang, X., Zhou, Q., & Sun, S. (2006). Determination of geographical origins of Chinese medical herbs by NIR and pattern recognition. Spectrosc Spectr Anal, 26(4), 629—632.
Liu, X. P., Feng, Y. C., Hu, C. Q., & Ding, L. (2008). Construction of universal quantitative models for determination of cefradine capsules. Chin J Pharm Anal, 28, 722–726.
Liu, Y., & Chen, K. (2012). Several common types of counterfeit and inferior drugs in Chinese medicinal materials market. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(8), 1089–1092.
Long, Y., Zhang, W., Wang, F., & Chen, Z. (2014). Simultaneous determination of three curcuminoids in Curcuma longa L. by high performance liquid chromatography coupled with electrochemical detection. J Pharma Anal, 4(5), 325–330.
Ni, Y. N., & Lin, W. (2011). Near-infrared spectra combined with partial least squares for pH determination of toothpaste of different brands. Chin Chem Lett, 22, 1473–1476.
Nugraha, A. S., & Keller, P. A. (2011). Revealing indigenous Indonesian traditional medicine: anti-infective agents. Natural Product Communications, 6(12), 1953–1966.
Obafemi, C., Sulaimon, T., Akinpelu, D., & Olugbade, T. (2006). Antimicrobial activity of extracts and a germacranolide type sesquiterpene lactone from Tithonia diversifolia leaf extract. Afr J Biotechnol, 5, 1254–1258.
Prabaningdyah, N. K., Riyanto, S., & Rohman, A. (2018). Application of FTIR spectroscopy and multivariate calibration for analysis of curcuminoid in syrup formulation. J Appl Pharm Sci, 8(3), 172–179.
Qu, N., Li, X. S., Y. Dou, H. M., & Y. Guo, Y. R. (2007). Nondestructive quantitative analysis of erythromycin ethylsuccinate powder drug via short-wave nearinfrared spectroscopy combined with radial basis function neural networks. Eur J Pharm Sci, 31, 156–164.
Rajashree, R., Divya, G., Sushma, P., Kanchan, I., & Sachin, K. (2013). Analytical Study of Curcumin Content in Different Dosage Forms Containing Turmeric Extract Powder and Turmeric Oleoresin. Int. J. Pharm. Pharm.Sci., 4(3), 182–185.
Rohman, A. (2012). Analysis of curcuminoids in food and pharmaceutical products. International Food Research Journal, 19(1), 19–27.
Rohman, A., A, N., E, L., & Sudjadi. (2014). Application of vibrational spectroscopy in combination with chemometrics techniques for authentication of herbal medicine. Appl Spectrosc Rev, 49(8), 603–613.
Rohman, A., Sudjadi, D, R., & A, N. (2015). A, Sudjadi, Ramadhani D, Nugroho A. Analysis of Curcumin in Curcuma longa and Curcuma xanthorrhiza Using FTIR Spectroscopy and Chemometrics. Res J Med Plant, 9(4), 179–186.
Schmidt, T. (2006). Structure activity relationship of sesquiterpene lactones. In A. Rahman (Ed.), Studies in natural product chemistry (pp. 309–392). Elsevier.
Sharma, K., Agrawal, S., & Gupta, M. (2012). Development and validation of UV spectrophotometric method for the estimation of curcumin in bulk drug and pharmaceutical dosage forms. Int J Drug Dev Res, 4(2), 375–380.
Shi, C. X., Yang, Y. W., Guo, Z. X., & Zhu, G. G. (2006). Quantitative analysis on Radix Salviae miltiorrhizae by NIR. J Chin Med Mater, 29, 897–899.
Shivali, G., Praful, L., & Vijay, G. (2012). A validated Fourier transform infrared spectroscopy method for quantification of total lactones in Inula racemosa and Andrographis paniculata. Phytochemical Analysis : PCA, 23(2), 171–176.
Siedle, B., Gustavsson, L., Johansson, S., Murillo, R., Castro, V., Bohlin, L., & Merfort. (2003). The effect of sesquiterpene lactones on the release of human neutrophil elastase. Biochem Pharmacol, 65, 897–903.
Sim, C. O., Hamdan, M. R., Ismail, Z., & Ahmad, M. N. (2004). Assessment of Herbal Medicines by Chemometrics - Assisted Interpretation of FTIR Spectra.
Siregar, C., Martono, S., & Rohman, A. (2018). Application of Fourier transform infrared (FTIR) spectroscopy coupled with multivariate calibration for quantitative analysis of curcuminoid in tablet dosage form. Journal of Applied Pharmaceutical Science, 8(08), 151–156.
Slamet, A., & Andarias, S. H. (2018). Studi Etnobotani dan Identifikasi Tumbuhan Berkhasiat Obat Masyarakat Sub Etnis Wolio Kota Baubau Sulawesi Tenggara. Proceeding Biology Education Conference, 15(1), 721–732.
Svante, W., Henrik, A., Fredrik, L., & Jerker, Ö. (1998). Orthogonal signal correction of near-infrared spectra. Chemom Intell Lab Syst, 44, 175–185.
Syed, H. K., Liew, K. Bin, Loh, G. O. K., & Peh, K. K. (2015). Stability indicating HPLC–UV method for detection of curcumin in Curcuma longa extract and emulsion formulation. Food Chemistry, 170, 321–326.
Syukri, Y., Martien, R., Lukitaningsih, E., & Nugroho, A. E. (2016). Quantification of Andrographolide Isolated from Andrographis paniculata Nees Obtained from Traditional Market in Yogyakarta Using Validated HPLC Quantification of Andrographolide Isolated from Andrographis paniculata Nees Obtained from Traditional Market. Indones. J. Chem., 16(2), 190–197.
Syukri, Y., Nugroho, A. E., Martien, R., & Lukitaningsih, E. (2015). Validasi Penetapan Kadar Isolat Andrografolid dari Tanaman Sambiloto ( Andrographis paniculate Nees ) Menggunakan HPLC. JSFK, 2(1), 8–14.
Wahyono, D., & Hakim, A. R. (2007). Effect of the curcuma plus® syrup on the pharmacokinetics of rifampicin in rats. Indonesian J Pharm, 18(4), 163–168.
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Published
2021-05-05
How to Cite
Alauhdin, M., Eden, W. T., & Alighiri, D. (2021). APLIKASI SPEKTROSKOPI INFRAMERAH UNTUK ANALISIS TANAMAN DAN OBAT HERBAL. Inovasi Sains Dan Kesehatan, 4. https://doi.org/10.15294/.v0i0.15
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